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KMID : 1161920160130020098
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Journal of Medicine and Life Science
2016 Volume.13 No. 2 p.98 ~ p.101
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Drug allergy
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Lee Jae-Chun
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Abstract
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Drug allergy is defined as the adverse drug reaction provoked by immunological mechanisms or roughly “type B” reaction, the mechanism of which cannot be explained by its own pharmacological mechanism. Drug allergy rarely happens in clinical practice, however, is usually dose-independent, unpredictable, and relatively severe in clinical manifestations. To find the safe alternatives and to prevent further reactions, the causative agents should be investigated. Complete history taking of exposed drugs and drug provocation tests are the mainstay in the diagnosis of the culprit drugs. The information of culprit drugs should be opened and shared among healthcare providers for the further drug safety, called as pharmacovigilance.
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KEYWORD
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Drug hypersensitivity, Allergy, Drug eruptions, Pharmacovigilance
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